Page 19 - HPIC-Magazine (Feb-2021)

News from Abroad

TREATING ACNE
Silab develops 3D model mimicking acneic skin

French cosmetics ingredients skin and to be used as a
maker, Silab, has developed a 3D screening tool for the deve-
in-vitro model of reconstructed epider- lopment of acne treatments,”
mis that mimics acneic skin. said Ms. Marine Laclaverie,
in vitro Innovation Project
Acne is an inflammatory skin dis- Leader.
ease involving four essential compo-
nents: hyperseborrhea (or overpro- The 3D model resulting
duction of sebum) combined with a from this work has enabled
modification of the composition of se- the company to demonstrate
bum; colonisation by Cutibacterium the pharmacological activi-
(C.) acnes, in particular the virulent dermis was treated simultaneously ties of its natural active ingredient,
phylotype IA1; hyperkeratinisation; with peroxidised squalene and C. Acnesium, used for treating the clini-
and a secreted inflammation. acnes phylotype IA1 obtained from cal signs of slight-to-moderate acne

Most 3D models mimicking ac- culture collection or isolated directly in adults.
neic skin independently use hyper- from acneic patients. The combina-
seborrhea or invasion by C. acnes to tion of these two factors induces acne- “Produced from the pericarps of
induce the characteristics of acneic like keratinocyte responses, such immature pomegranates, Acnesium
skin. However, as these two factors as hyperkeratinisation and inflam- restores homeostasis to acneic skin
are inter-related at the early stages mation, thereby providing a model by targeting the four major compo-
of the pathology, Silab researchers exhibiting all the characteristics of nents of this pathophysiology: it re-
sought to develop a 3D model com- acneic skin. stores sebaceous gland activity to
bining sebum alteration and invasion normal; controls colonisation by C.
by C. acnes. “The detailed characterisation of acnes phylotype IA1; has a keratoly-
this new in-vitro model proves that tic action; and reduces inflammation,”
In this model, reconstructed epi- it is totally suitable to mimic acneic the company informed.

LEVERAGING SYNERGIES
IFF unveils new branding upon closing DuPont

segment merger

US-based fragrances & flavours global leader in ingredients and solu- science. The company’s purpose,
maker, IFF, has launched a new tions for the food & beverage, home & meanwhile, is ‘Applying science and
brand identity to reinforce its leader- personal care and health & well- creativity for a better world’, which
ship role in the global value chain ness markets with estimated pro reflects its commitment to pushing
for consumer goods and commercial forma revenue of more than $11-bn. boundaries for a more sustainable
products, following the completion of The complementary portfolios will future. Thirdly, IFF’s central vision
its merger with DuPont’s Nutrition & give the company leadership within has been revealed as ‘Be the partner
Biosciences business. the taste, texture, scent, nutrition, for essential solutions’, reflecting its
enzymes, cultures, soy proteins and leadership role in the global value
The move to bring together IFF
and DuPont’s Nutrition & Bioscien- probiotics ingredients categories. chain for consumer goods.
ces arm was announced in May 2020 IFF’s new brand identity and tag- The company’s business divisions
and completed on February 1, 2021. line will be ‘Where science and crea- will now be configured as Nourish
The combined company continues to tivity meet’, which seeks to capture (combining taste, food and bever-
operate under the name IFF.
the company’s longstanding focus on age), Scent, Health & Biosciences
The merger is said to create a the interplay between artistry and and Pharma Solutions.
Home, Personal & Institutional Care India February 2021 19