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COLLABORATION
L’Oréal inks skin microbiome partnership with

Micreos

French beauty giant, L’Oréal, has Micreos’ pharma development dermatitis,” explained dermatolo-
signed a license agreement with programme includes endolysins gist, Dr. Peter Lio, Scientific Advisor
Micreos, a Dutch biotech company that target Staphylococcus bacteria, for Micreos and Scientific Advisory
specialising in biological therapies which cause or aggravate a broad Board member for the American
based on phage (a virus that infects range of health issues, including National Eczema Association.
and replicates within bacteria) and skin conditions. The company re-
endolysin (enzymes that originate cently enrolled the first patients in ‘XZ.700’ is one of several endo-
from bacteriophages) technology. a Phase I/IIa, randomised, double- lysins Micreos has in its portfolio. A
L’Oréal aims to develop new cosmetic blind, placebo-controlled, parallel structurally similar endolysin, ‘SA.100’,
solutions targeting the skin micro- treated dose-ranging study to assess is used in the company’s over the coun-
biome, the community of bacteria and the safety and efficacy of their endo- ter (OTC) products for inflammatory
microorganisms that live on the skin. lysin ‘XZ.700’ in patients with mild skin disorders (e.g., acne and rosacea),
to moderate atopic dermatitis. The in particular the Gladskin range, which
Under the terms of the deal, Mi- study marks the world’s first evalua- has been on the European market since
creos will give L’Oréal access to one tion of a pharmaceutical endolysin for 2013 and was launched in the USA in
of its endolysins of interest in the topical use in humans. January this year.
cosmetic field. “With this techno-
logy, it is possible for the first time to “The targeted removal of one “The agreement with Micreos
target only unwanted bacteria in the particular bacterial species, S. aureus, opens up a very promising field in
skin flora – responsible for many skin from the skin microbiome, while high-tech cosmetics,” said Mr. Lau-
problems – while sparing the good preserving the beneficial ones is a rent Attal, Executive Vice-President
ones,” L’Oréal informed. fundamental new way to treat atopic Research & Innovation of L’Oréal.

TACKLING POLLU TION
Beiersdorf launches Nivea bottle with lower plastic

content

Germany’s Beiersdorf, the owner company announced the Paris Climate Agreement, Beiers-
of Nivea brand, has launched a new that it was on track dorf said it is looking to minimise its
Nivea bottle with 50% less plas- for 90% of its PET environmental footprint.
tic. The bottle and cap of the new bottles in Europe
‘Nivea Naturally Good Body Lotion’ to include recycled Mr. Jean-Francois Pascal, Vice
have been designed to use half the plastic material by President Corporate Sustainability at
plastic required for its standard body the end of this year. Beiersdorf, said, “As we strongly be-
lotion packs. The very thin bottle has Beiersdorf said this measure alone lieve the global plastic problem can-
a uniquely shaped base that can be will save more than 1,200 tonnes of not be solved in silos, but a broader
easily squeezed and rolled up tightly fossil-based virgin plastic per year. collaboration and joined forces are
in a similar manner to a toothpaste needed, we are taking action beyond
tube, providing better restitution. Beiersdorf’s action falls in line our own business. We are teaming
The bottle is fully recyclable after with a concerted push amongst cos- up with our suppliers, trade partners,
usage and because of the thinner, metic and personal care manufac- NGOs, scientific institutions and also
lighter profile, provides improved turers for authenticity and account- with other players in our industry.
pallet utilisation during transit. ability in their sustainability efforts. We want to really drive the topic
Aligning goals with governmental forward and contribute to the change
Further to this new reveal, the and NGO climate change targets and we need within a broader context.”
Home, Personal & Institutional Care India November 2020 19